Rachel McAdams, 41, will forever be “Regina George“! The Canadian actress shot to stardom after playing the “Plastics” leader alongside Lindsay Lohan, Lacey Chabert and Amanda Seyfried in 2004’s Mean Girls, and she just revealed she would be open to revisiting the character in the future. “It would be fun to play Regina George later in her life and see where life took her!” Rachel said on the “Heroes of Health: COVID-19 Stream-a-thon” on Saturday, April 18.