Vida y Estilo, that she uses Biotulin as a natural alternative to Botox. “Letizia is already by nature a very beautiful woman. She knows that plastic surgery is something that would only hurt, something you do not need,” Telma revealed, adding her sister “completely rejects Botox treatments.”With such a high profile fan following, the serum must be next-level, so what's the deal? It's said to smooth skin on an organic basis as part of your daily skincare routine.