Rebecca Rubin Film and Media Reporter “Indiana Jones and the Dial of Destiny” is gunning for the top spot on box office charts. The fifth and final adventure to star Harrison Ford as the legendary, globe-trotting explorer is targeting at least $65 million from 4,500 North American theaters in its opening weekend. The latest Indy installment is also debuting day-and-date at the international box office, where it’s aiming to add $80 million for a global start of $145 million to $150 million. Those ticket sales are decent, especially for the fourth sequel to a decades-old property that’s aimed at older audiences. But Disney spent a mind-boggling $295 million to bring the action-adventure to life. That’s not including marketing costs, such as a no-expense-spared premiere and afterparty at the Cannes Film Festival where much champagne was tippled. Even in the best circumstances, it’ll take a heroic feat — and a lot of nostalgia from long-time fans of the series — for “Indiana Jones 5” to turn a profit in its theatrical run.