The world is waiting for you, so says longtime Amazing Race host Phil Keoghan, who is once again gearing up for another season of the Emmy-winning CBS series.
02.09.2022 - 11:49 / dailyrecord.co.uk
A new method to predict Alzheimer’s risk has been developed by researchers, who believe that spotting the condition early could help speed up the creation of new treatments for the disease.
The method can help identify those who are at greater risk of developing Alzheimer’s disease. This means that they could get tested before symptoms appear.
Using a genetic predictor, the researchers looked at 7.1 million common DNA variants and determined an individual's risk based on their specific DNA variants.
The researchers initially looked at tens of thousands of people from a past study and their method was refined and validated with data from more than 300,000 further people.
Some experts have suggested that spotting the disease early could help uncover potential treatments. Past attempts to uncover possible treatments may have been unsuccessful because they involved patients whose disease was too advanced to be treated, experts suggest.
While some treatments can ease symptoms, developing treatments that prevent or slow disease progression has been more challenging.
Better methods to identify people at high risk of developing the condition could aid treatment research.
People with Alzheimer’s experience gradual loss of memory and other cognitive functions.
Senior author Dr Amit Khera said: “We developed a genetic predictor of Alzheimer’s disease associated with both clinical diagnosis and age-dependent cognitive decline.
“By studying the circulating proteome of healthy individuals with very high versus low inherited risk, our team nominated new biomarkers of neurocognitive disease.”
In the new study Manish Paranjpe of the Broad Institute of MIT and Harvard in the US and colleagues analysed data on 7.1 million common DNA variants –
The world is waiting for you, so says longtime Amazing Race host Phil Keoghan, who is once again gearing up for another season of the Emmy-winning CBS series.
New Order and Pet Shop Boys kicked off their joint North American tour over the weekend – see footage, pictures and the setlists from their opening night below.The British synthpop titans’ tour got underway at Toronto’s Budweiser Stage on Saturday (September 17) following delays due to the COVID pandemic.The Unity Tour’s revised dates include guest DJ Paul Oakenfold and take in an additional date at Brooklyn’s Barclays Center in New York. Head here for any remaining tickets.New Order opened their set on Saturday with ‘Regret’ and wrapped with a cover of Joy Division‘s ‘Love Will Tear Us Apart’.Pet Shop Boys, meanwhile, opened with ‘Surburbia’ before closing with ‘Being Boring’.
Bad Bunny has shared a new music video for ‘El Apagón’ alongside a documentary about his native Puerto Rico.The documentary, titled Aquí Vive Gente (People Live Here), plays after the official video for the new single on YouTube, and is narrated by Bianca Graulau.In the short film, a plethora of issues in Puerto Rico are discussed, including rising rent prices, social and economic issues and the development of luxury accommodation.Watch the music video for ‘El Apagón’ and the Aquí Vive Gente (People Live Here) documentary below.Bad Bunny released his new album ‘Un Verano Sin Ti’ in May of this year. In a four-star review of the album, NME wrote: “Of course, 23 tracks is a lot to take in, especially if you’re listening to ‘Un Verano Sin Ti’ on the bus to work rather than a balmy beach.
Six countries have not received invitations to the Queen's state funeral on Monday September 19.
Kelly Clarkson is joined by some special guests as she returns for a star-studded season 4 “Kelly Clarkson Show” premiere on Monday.
Todd Spangler NY Digital Editor Altice USA is making changes at the top: The cable operator announced that it has recruited Comcast veteran Dennis Mathew as CEO. Matthew takes over effective Oct. 3, assuming the CEO role from Dexter Goei, who has been named executive chairman of the board of directors. All of Goei’s direct reports will report to Mathew. Altice USA founder and current chairman Patrick Drahi will remain a director on the board. The No. 4 U.S. cable operator said it made the move to hire a new CEO “given Mr. Goei’s intention to return to Europe with his family.” Goei has worked for France’s Altice since 2009, leading the telecom company’s entry into the U.S. market through the acquisitions of Cablevision Systems and Suddenlink Communications, which now comprise Altice USA.
EXCLUSIVE: The story of the American Basketball Association (ABA), which was responsible for stars such as Julius Erving, is to be told in a new docuseries for Amazon.
Ben Stiller and Sean Penn are among 25 Americans who are permanently banned from entering Russia.
Russian Foreign Affairs Ministry’s website (September 5), the personal sanctions are said to be in response to US sanctions against Russia following the country’s invasion of Ukraine.A translated statement reads: “In response to the ever-expanding personal sanctions on Russian citizens by Joe Biden’s administration, a permanent ban to enter the Russian Federation has been imposed on another group of US Congress members, high-ranking officials, members of the business and expert community and cultural figures.”Both Stiller and Penn have shown support for Ukraine amid the country’s ongoing war with Russia. In June, Stiller, a goodwill ambassador for the United Nations High Commissioner for Refugees (UNHCR) met with Ukrainian president Volodymyr Zelenskyy and also visited occupied settlements in Kyiv.A post shared by UNHCR, the UN Refugee Agency (@refugees)In a video on Instagram, Stiller said: “I’m meeting people who’ve been impacted by the war and hearing how it’s changed their lives.
Ethan Shanfeld Ben Stiller and Sean Penn have been permanently banned from entering Russia, the Kremlin announced Monday. The actors are listed among 23 other United States citizens newly barred from the country, including Senators Kirsten Cinema, Richard Scott, Patrick Toomey Jr. and Mark Kelly, as well as Deputy Ministers of Trade Matthew S. Alexrod, Don Graves, Thea Kandler and Jeremy Pelter, and Minister of Commerce Gina Raimondo. An official statement from the Ministry of Foreign Affairs of the Russian Federation, translated to English, reads: “In response to the ever-expanding personal sanctions by the Biden Administration against Russian citizens, against another group of persons from among members of the U.S. Congress, high-ranking officials, representatives of the business and expert communities, as well as cultural figures (25 people), a ban on entry into the Russian Federation on a permanent basis. The following is a list of names of American citizens who are included in the Russian ‘stop list,’ based on the principle of reciprocity.”
Sean Penn and Ben Stiller today were among 25 “high-ranking officials, representatives of the business and expert communities, as well as cultural figures” banned from Russia today by that country’s foreign ministry.
It looks like Austin Swift might have a new girlfriend!
Vladimir Putin demands absolute fealty to the Russian state, and woe to anyone who defies him.
EXCLUSIVE: Allen Leech (Downton Abbey, Bohemian Rhapsody) and India Mullen (Normal People, Brassic) will lead the cast of an Irish drama series for AMC Networks’ Sundance Now and local broadcaster Virgin Media Television, we’ve learned.