The Flight Attendant.” The new season will premiere on Thursday, April 21.The dark comedy series focuses once again on lead character Cassie Bowden, played by Kaley Cuoco. Bowden is living a sober life in Los Angeles while moonlighting as a CIA asset in her free time when she is assigned overseas, leading her to accidentally witness a murder. Once again, Bowden is entangled in another sprawling network of international intrigue.The series stars Cuoco, and Season 2 will bring back series regulars Zosia Mamet, Griffin Matthews, Denis Akdeniz and Rosie Perez, as well as returning recurring guest stars T.R.