At the end of Meg Ryan‘s beguiling and grown-up new romantic comedy What Happens Later, a simple dedication card shows on screen that says “To Nora.” And for star, director and co-writer Ryan, that says it all. After an eight-year absence from the screen, Ryan has returned, both in front of and behind the camera, to a genre that made her a huge star thanks also in large part to the late great Nora Ephron, whose trio of collaborations with Ryan — When Harry Met Sally (directed by Rob Reiner), Sleepless in Seattle and You’ve Got Mail — truly defined what a joyful experience a romantic comedy could be when in the right hands.