Brad Pitt and Angelina Jolie's separation in September 2016 shocked Hollywood to its core because not even in our wildest imagination did we picture a scenario where Brangelina wasn't endgame. While there's still no definitive confirmation regarding the reason for their split, it was Brad's rumoured altercation with their eldest son Maddox Jolie-Pitt during a flight that caused the rift that the couple were unable to recover from.