Amanda Seyfried has just locked in her next big role as Elizabeth Holmes, the former founder and CEO of Theranos, in the Hulu limited series . The actress replaces Kate McKinnon, who was originally cast in the true-crime drama.Adapted from the ABC Radio podcast about the rise and fall of Holmes and her Silicon Valley-based company, will chronicle the true story of an American businesswoman who managed to raise billions of dollars over false claims of developing a revolutionary blood test.