Gene Maddaus Senior Media WriterTime’s Up will lay off most of its 25-member staff at the end of the year and its interim CEO will depart, as the women’s rights organization looks to “reset” in the wake of a debilitating conflict-of-interest scandal.The organization announced the changes on Friday. The group also released a 54-page report that seeks to address the organizational failures that contributed to its mishandling of sexual harassment charges against New York Gov.